Merritt’s Neurology 14th Edition 2022 pdf

  Merritt’s Neurology 14th Edition 2022 pdf



Development Editor: Ariel S. Winter

Acquisitions Editor: Chris Teja 

Editorial Coordinator: Tim Rinehart 

 Editorial Assistant: Maribeth Wood 

Marketing Manager: Kirsten Watrud 

 Senior Production Project Manager: Alicia Jackson  

Manager, Graphic Arts and Design: Stephen Druding

 Art Director, Illustration: Jennifer Clements Senior Manufacturing Coordinator: Beth Welsh

 Prepress Vendor: Absolute Service, Inc.

   Pages:  5907                                                                                                                                  Language: English                                                                                                   Format: PDF                                                                                                                                                        Size 138 MB

Contents :
Section Editor: Mitchell S. V. Elkind    
Worldwide Epidemiology of Neurologic Disease 
 Jennifer Sevush-Garcy and Mitchell S. V. Elkind  
  The Classification of Disease: What is a Neurologic Disorder  ?
. Estimating Disease Burden  
 Life Expectanc
  The Shifting Character of Neurologic Disease Over Time The Epidemiologic        Transition and the Double Burden of Disease  
. Chronic Neurological Diseases 
 Access to Care  
Sociocultural Differences in Interpretation of Disease  

2 Global Delivery of Neurologic Care 
 Hiral Shah, Serena Spudich, and Kiran T. Thakur   
 Gaps in Global Access to Neurologic Care 
 Components Required for Delivery of Neurologic Care
 Challenges in Addressing Neurologic Disorders Stigma Related to Neurologic..           Disorders Challenges in Health-Seeking Behavior
 Limited Global Access to Diagnostics and Therapeutics for Neurologic Disorders 
Gaps in National Policies and Guidelines for Brain Health Approaches and Strategies.. to Improve Delivery of Neurologic Care Globally 
Collaborative Partnerships and Coordinated Action Improving Access to Neurologic..    Care: Primary Care Workforce
 Telemedicine and Information and Communication Technology 
.  Synchronous Approaches 
 Asynchronous Approaches 
 Training Approaches to Build Capacity
 Community Engagement
  Programs Aimed to Raise Public Awareness

Section Editor: James M. Noble  
 3 Neurologic History Taking, Localization, and Differential Diagnosis 
 James M. Noble  


When H. Houston Merritt first published this Textbook of Neurology in 1955, he was the sole author. The book became popular, and he revised it himself through the fourth edition. The body of neurologic knowledge increased and, in the fifth edition, he finally accepted contributions from colleagues. Even then, he wrote most of the book himself, and he continued to do so for the sixth edition despite serious physical disability. He died in 1979, just as the sixth edition was released for distribution. The seventh edition, published and edited in 1984 by Lewis P. Rowland, was prepared by 70 of Merritt’s former students, almost all with ties to Columbia University. Thirty of them headed neurology divisions or departments, and others had become distinguished clinicians, teachers, and investigators.

 That edition established Merritt’s legacy as a singular leader whose career had set models for clinical investigation (when it was just beginning), clinical practice, teaching, editing books and journals, administering departments and medical schools, and commitment to national professional and voluntary health organizations. Just as Houston Merritt did, “Bud” Rowland served as chief editor for the next five editions of the book. During that 30-year span, Merritt’s Textbook of Neurology became firmly established as a classic the world over. At the same time, as codirector at the Neurological Institute of New York at Columbia University, Rowland trained and inspired a new generation of academic and practicing neurologists, edited the journal Neurology and served as an associate editor for The New England Journal of Medicine, and was a prolific researcher and writer in his own right, authoring hundreds of scientific articles. In 2016, Rowland handed off the lead editing duties of the 13th edition of Merritt’s textbook to Drs Elan D.

 Louis and Stephan A. Mayer while continuing to serve as a coeditor. The 13th edition represented a thorough modernization and substantial reboot compared to previous editions. We substantively broadened the authorship base beyond those who had trained or worked at Columbia, tapping into the best expertise across the country. More importantly, we added new focus to the mission of Merritt’s Textbook of Neurology: While retaining its best elements and traditions, we aimed to create the essential modern neurology textbook with a global worldview. Gone were the largely descriptive chapters and black and white photos of prior editions. The 13th edition blossomed into full color and featured a completely revamped table of contents, including an opening chapter entitled “Worldwide Epidemiology of Neurologic Disease,” new chapters related to acute neurology and neurocritical care, and a new section in the front of the book entitled “Common Problems in Neurology.” The 13th edition also emphasized patient management based on evidence-based guidelines, helpful diagnostic and treatment algorithms, management checklists, and practical pearls.

We added for the first time numbered citations to back up all diagnostic and management recommendations based on high-quality clinical trials, evidence-based practice guidelines, or meta-analyses. Lewis P. Rowland died in 2017 at the age of 91 years, 1 year after publication of the 13th edition. Clinical neurology continues to rapidly advance on multiple fronts, and we welcome Dr James Noble of Columbia University as a coeditor. Dr Noble, a cognitive neurologist and experienced educator, taught in clinical conferences with Dr Rowland until just weeks before his death. His inclusion builds on the longstanding tradition of Merritt’s Neurology serving as an important tool in clinical neurology education. As students and admirers of “Bud” Rowland, we are proud to dedicate this 14th edition of Merritt’s Textbook of Neurology to Dr Rowland. As with any dynamic book, the list of authors has continued to expand, to more than 180 authors for this 14th edition. Although many were trainees or have worked at Columbia University, we have continued to invite authors who are world-recognized leading experts. Along the same lines, we have sought to maintain Houston Merritt’s literary style: direct, clear, and succinct writing; emphasis on facts rather than unsupported opinion; and ample use of illustrations and tables. Other changes with this 14th edition of Merritt’s include the continued evolution of the book’s unique and colorful visual style, featuring even more algorithms, flowcharts, illustrations, and videos. The book is designed for access from tablet, phone, and computer screens with enhanced navigation, search, and annotation tools.

 The chief idea for our readers is to provide curated, clinically rich information at the bedside, office, and even virtual clinical session—when and where clinicians need it. The Internet is full of information, but it is difficult to sort through. Merritt’s provides trusted and cohesive information from expert all in a single place. This edition of Merritt’s is fully updated and includes comprehensive revisions reflecting remarkable progress made in recent years in neurology research, including new and emerging treatments for diseases previously without effective pharmacotherapy. New material includes updates on imaging and interventional therapy for stroke, the latest approved agents for migraine, epilepsy, and multiple sclerosis and new material on neurologic care in the developing world, neuro–coronavirus disease, septic encephalopathy, and addiction medicine. We thank all the authors for their devoted and skillful work. We also thank the many section editors for their thoughtful guidance and painstaking efforts. This project would never have moved forward without the help of many people at Wolters Kluwer. Indeed, a full roster of people has been involved in the project, from its conception to completion. These include Chris Teja (acquisitions editor), Tim Rinehart and Ariel S. Winter (product development editors), Maribeth Wood (editorial assistant), Stephen Druding (design coordinator), Harold Medina (production project manager), and Kirsten Watrud (marketing manager). Special thanks should go to Andrea Vosburgh, who initially brought the 13th edition and the concept of a complete overhaul of the book to fruition. In addition to Dr Lewis P. Rowland, Dr Louis also dedicates this book to his late father, Dr Sydney Louis, an academic neurologist who inspired his career in neurology—a role model as a humanist, an educator, a perceptive clinician with a keen eye for nuance and detail, and a patient-centered physician.

 Countless friends and colleagues with whom we have worked at The Neurological Institute of New York at Columbia University over the years deserve credit for inspiring us, most notably John Brust, E. Sander Connolly, Stanley Fahn, Matthew E. Fink, Laura Lennihan, Linda Lewis, Karen Marder, J. P. Mohr, Timothy Pedley, Robert A. Solomon, and Olajide Williams. Dr Louis would like to thank Bettina Evans, at Yale University, whose tireless efforts early on ensured that spreadsheets would be organized and authors contacted in a timely manner, and Dr David Hafler, chair of the Department of Neurology at Yale, for providing support for the project as this edition was being prepared. Finally, we would like to personally dedicate this book to the spouses and children of all the contributors and especially to our own families. Dr Louis would like to gratefully acknowledge the wise advice and loving support of his wife, Dr Avra Louis, and that of his children, Devin, Ravi, and Kiran. The Mayer family includes Dr Elissa Fory and children, Philip, Catherine, Chloe, and Soren. Dr Noble thanks his family for support including his wife Anne and their children Josephine, Salvatore, Benicio, and Beatrice. 


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