Unusual Uses of Common Drugs 2015 pdf
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Unusual uses of common drugs
By
PHARMACIST : Ahmed Mohammed Yossef
Pages: 216
- Language: English
- Format: PDF
- Size : 4.40 MB
Contents :
. Acetyl salicylic acid
. Amitriptyline
. Betamethasone
. Bromocriptine
. Bupropion
. Calcium
. Cabergoline
. Combined oral contraceptive
. Dexamethasone and betamethasone
. Diltiazem
. Domperidone
. Erythromycin
. Finasteride
. Folic acid
. Gonadotropins
. Insulin
. Liraglutide
. MegestrolAcetate
. Metformin
. Metronidazole
. Nifedipine
. Prednisolone
. Propranolol
. Sildenafil
. Sodium bicarbonate
. Spironolactone
. Sulfasalazine
. Tadalafi
. Topiramate
. Trimethoprim-Sulfamethoxazole
. Vitamin D
PREFACE
Unusual uses of common drugs is a new vision to
experience the hidden side in medications effect.
It is the indications that health care provider not used
to deal with it. Some indications may be approved by
FDA other indications may be not yet approved.
Unusual uses of common drugs differ from off-label uses
that some indications approved by FDA. health care
provider awareness of these unusual indications leading
to the best counselling to the patient and let him use
these medications in best way, also give health care
provider many choices in some critical cases.
Unusual uses of common drugs open the health care
provider’s mind towards a new ways to the effect of
medications.
A salicylate drug, often used as an analgesic to
relieve minor aches and pains, as an antipyretic to
reduce fever, and as an antiinflammatory medication.
Aspirin also has an antiplatelet effect by inhibiting
the production of thromboxane, which under
normal circumstances binds platelet molecules
together to create a patch over damaged walls of
blood vessels. Because the platelet patch can
become too large and also block blood flow, locally
and downstream.
Pregnant women at high risk for
preeclampsia should take low-dose aspirin (75mg81mg) every day after their first trimester .
Preeclampsia is a complex condition that occurs in
pregnant women and involves an increase in blood
pressure and excess protein in the urine after 20
weeks of pregnancy.
Daily low-dose aspirin in middle and late
pregnancy can significantly reduce the occurrence
of preeclampsia among these women and it can
lower the risk of preterm birth or low birth weight
resulting from the pregnancy-related condition
because aspirin helps blood flow between the
placenta and the fetus.
High or normal doses (>325 mg) block production
of prostacyclin and thromboxane, and low-dose
aspirin (60–83 mg) results in selective block of
thromboxane production, and favors the
prostacyclin (vasodilation) pathway.
This provides the basis for the use of low-dose
aspirin to forestall or prevent pregnancy-induced
hypertension. Importantly, low-dose aspirin does
not completely inhibit thromboxane and does not
completely ‘spare’ prostacyclin. One group of
investigators found that 81 mg of aspirin inhibited
thromboxane by 75 percent, but also inhibited
prostacyclin by approximately 20 %.
